Khaini damages chromosomes

Asian Pac J Cancer Prev. 2009 Oct-Dec;10(4):715-6.

Khaini chewing damages chromosomes 2q, 3p and 21q: occurrence in a South Asian population.

Choudhury CR, Chowdhury A, Prasad RB, Shibahara T.

International Centre for Tropical Oral Health, Poole Hospital NHS and Bournemouth University, England.

Chewing Khaini damages chromosomes, in the form of loss of heterozygosity (LOH), identified on the long arm of chromosome 2 (2q), the short arm of chromosome 3 (3p) and the long arm of chromosome 21 (21q) of oral cancer cases who had quid chewing habit of more than 10 years duration, and chewed 10-15 times a day.